Headquartered in Northern Italy, ICE Group is a globally integrated business comprising three major production and refinement facilities in Italy, Brazil and India.

At our headquarters in Reggio Emilia, Northern Italy, we use the latest technology to produce bile acid derivatives for the pharmaceutical market. The site, situated around 150km from Milan, includes offices, laboratories and production facilities.
The manufacturing facility is equipped with multiple glass-lined stainless-steel multi-purpose reaction vessels, centrifuges and vacuum and fluid bed dryers.

Our other Italian site is located at Basaluzzo, in the industrial heartland of northern Italy. The Basaluzzo site converts cholic acid shipped from the BBA plant in Brazil into Ursodeoxycholic Acid (UDCA).

BBA ‘Indústria Química Ltda’ is our Brazilian operation, which has grown to become the largest collector of bovine bile, horns and hooves in the world. Situated in Jacarezinho, in the southern Brazilian state of Paraná, the facility handles thousands of tons of concentrated bile and hoof and horn, annually.

The facility manages all the production steps from the collection of Bovine Bile to the production of Cholic Acid. It is equipped with state-of-the-art stainless-steel reaction vessels, agitated nutsche filter dryers and a centrifuge with considerable capacity.

Strategically located on the Transbrasiliana Highway, with its own logistics fleet, it is the centre of the South American bile supply network.

Raichem is our Indian full-service API plant for the production of Ursodeoxycholic Acid (UDCA). Established in 2009, the construction of the Raichem facility was completed in 2015. It is located in the Raichur Industrial Growth Center, in the Karnataka region, India.

The facility is well equipped with both glass-lined stainless-steel multi-purpose reaction vessels and agitated nutsche filter dryers.

The site has a modern laboratory, capable of handling all the testing required for analysis of APIs and Intermediates. To maintain quality standards, the plant has well defined procedures and systems in place in compliance with the requirements of Current Good Manufacturing Practices (cGMP).

Located in Piacenza, Italy, Riaz is our facility for processing the slaughterhouse by-products of bovine, ovine and porcine origin.

The continuous production cycle enables us to process raw materials supplied by partners across Europe to produce components for the chemical, pharmaceutical and cosmetic industries.

Riaz has invested heavily to minimize its environmental footprint through recycling processes and continuous investment in research and development.

Roth is our facility for the purchase, collection and processing of raw material liquid bovine bile in North America. It also serves as a distribution point of horn and hoof to U.S. customers.

The site has two plants in Amarillo, Texas (HQ) and Adel, Iowa. Both sites work together with suppliers and shared logistics to strategically cover both the North and South of the US, with Houston seaport as a strategic hub to trade with overseas partners and with other Group facilities further down the supply chain.

Arennis, CVF and PBP are involved in the collection and concentration of bile across South America. Using their own logistics fleet, they collect bile from a network of 150+ suppliers across the region and deliver it to our primary facilities for preliminary processing.

Arennis is our Argentinian Facility, situated in Buenos Aires and Clorinda, Formosa state. CVF is headquartered in La Paz in Uruguay and PBP is located in Luque, Paraguay.